The number of injuries caused by crashes on the Appin Road has dropped by 64 per cent since 2009, according to statistics from Roads and Maritime Services.
The recently released crash history of the road looks at the period from 1996 until June 2012.
In recent years, the number of motorists injured in crashes on Appin Road has dropped from 31 in 2009 to just 11 by 2012 - a drop of 64 per cent.
The worst year for casualties was 2000, when 42 people were injured.
The 2012 figure for casualties is the lowest since 1996.
Fatalities on the road have remained low in recent years, with just one recorded each year between 2009 and June 2012.
However, the 2012 figures do not include the deaths of eight-year-old Brock Anderson and 19-year-old Thomas Scott-Dobie, who died in separate crashes in September and October, 2012.
These deaths led to the road receiving attention from the NSW government. A review of speed zones was undertaken earlier this year and a safety study on Appin Road is expected to be released early in 2014.
Work on improving the safety of Appin Road has included rebuilding the road west of Westcliff Colliery, resurfacing sections of the road, adding crash barriers and repairing Appin Road Bridge.
The RMS crash history splits the road into three sections - from Ambarvale to just north of Appin township; the township itself; and east of the township to Bulli Tops. The last section has the worst crash record.
In the five years to June 2012, there were 144 crashes on Appin Road, resulting in three fatalities and 113 injuries. The stretch from the township to Bulli Tops - most of which is a 100km/h zone - saw 83 of the 144 crashes and 72 of the reported injuries.
This part of the road was also where all the fatalities occurred.
The crash history states that 56 per cent of these crashes involved a single vehicle and 45 per cent featured vehicles travelling at an "inappropriate speed".