One northbound lane is closed on the Princes Motorway at Mount Ousley following a glass spill.
Glass is scattered along the highway just past New Mount Pleasant Road. A spokeswoman from the Transport Management Centre said the source of the debris was not known.
Emergency services and traffic crews are on the scene.
Motorists should reduce speed and exercise caution.
Southbound drivers should also be wary of a satellite antenna on Mount Ousley Road near Picton Road at Cataract.