Newcastle and St George Illawarra were the first teams to officially declare their interest for a licence for the inaugural women's NRL tournament in 2018.
The race for six licences could be hotly contested, with up to 14 clubs potentially bidding to be involved in the opening season.
Newcastle CEO Philip Gardner said the Knights wanted in on the ground floor of the competition.
"This is great for the game ... while there is still a lot to be worked out to ensure long-term success for the women's game, we will be putting in an application to have the Knights represented in this competition," he said.
His Dragons counterpart Peter Doust followed suit, saying "St George Illawarra and particularly Illawarra Rugby League have been instrumental in the development of interest in women's rugby league over many years now, and we have certainly expressed our interest already to the NRL about having a St George Illawarra Dragons team as part of the inaugural women's premiership".
Fairfax Media understands that only two clubs, Gold Coast and Canberra, have ruled themselves out of the running, and neither have done so for on-field reasons.
The Titans said through a spokesperson that they are definitely interested, but the timing is "probably not right" due to the current ownership situation. What's more likely is that the Titans attempt to acquire a license during the second wave of applications, when the competition inevitably expands either in 2019 or beyond.
Canberra will also target the league's sophomore season, with the club in the process of securing funding to build a new centre of excellence to incorporate a women's team. That won't be up and running until the middle of next year.
Melbourne CEO Dave Donaghy conceded the club has "some challenges with facilities in Victoria" - their home base of AAMI Park is already shared by clubs across the A-League, W-League, Super Rugby, AFL and AFLW - but are keen to get involved.
"From a Storm point of view, we've definitely demonstrated an ability and a desire to be a leader in all sport - not just male sport," Donaghy said.
"I think we've got the proven track record ... we'll certainly give it some serious consideration. Anything we do, we do it properly."
The club has proven this in the Super Netball, where their joint-venture club the Sunshine Coast Lighting are the reigning champions.
Wests Tigers boss Justin Pascoe said the club "welcomed" the announcement.
"The involvement of women at our club is very important for our club on and off the field," Pascoe said. "We look forward to getting more information and are keen to be part of the competition."
Parramatta will likely also be one of the clubs vying for a licence.
"As a club we are very supportive of the NRL's decision to move ahead in the women's game," Eels boss Bernie Gurr said. "The NRL has sensed that the clubs are keen to provide an elite pathway and a shortened competition is a smart way to start. We will certainly be interested in participating from 2018 onwards.
"Our junior league has seen strong growth in female participation so we see this as a great opportunity to expand an important part of our game even further."
The Bulldogs, runners-up in the inaugural Tarsha Gale Cup - an under-18s nine-a-side competition - are "very much behind the idea" and will make a call when they have more details. It's a sentiment shared by the Sharks. "We're interested but we're not going to commit at this stage," a Cronulla spokesperson said.
South Sydney is "very keen" to be involved in the inaugural season, and would likely have a strong talent pool to draw from, with the Redfern All Blacks winning the women's state competition this year.
Penrith's high-performance manager Matt Cameron stated: "[The club is] passionate about the growth of rugby league and building a strong women's development pathway. The club would certainly look into the viability of a women's team."
Sydney Roosters CEO Joe Kelly said the club was keen to be involved in the development of the women's game.
"The Sydney Roosters fully endorse this initiative which will provide a pathway for female players. The Club will be exploring the possibility of pursuing a licence for a women's team in 2018," he said.
A spokesman for the Broncos said that the club had supported the idea of women's competition for some time, as does their CEO Paul White, and they will definitely consider their options for 2018.
Cowboys officials, currently overseas, were not contactable. Fairfax Media was awaiting responses from the Warriors and Manly at the time of publication.