"Fair treatment" for Dragons player Jack de Belin is a key plank of One Nation's policy for the Illawarra.
Slowing the region's population growth via cuts to immigration is also on the One Nation agenda.
The party's state leader and candidate for the NSW upper house, Mark Latham - a St George Illawarra fan - is due to visit the region on Thursday to launch a "seven point Illawarra plan".
"Too often the region has been ignored in NSW politics, resulting in over-development and congestion and a lack of jobs and infrastructure," Mr Latham said.
"Labor and Liberal have treated the Illawarra as a dormitory area for Sydney, when good public policy should be helping the region develop as a self-sufficient economy and community."
The plan also includes a promise of a $200 million Illawarra Hospital Development Fund with priority given to upgrading Wollongong Hospital and the creation of an extra 2000 commuter car parking spaces over the next two years.
Mr Latham has also sees one of the key needs for the region is supporting the St George-Illawarra Dragons in their struggle to achieve fair treatment for Jack de Belin, who has been rubbed out of the game for 18 months".
"One Nation will move legislation in the NSW Parliament to prevent sporting codes and other employers from punishing people without evidence of wrongdoing prior to criminal matters being determined by the NSW judicial system," the plan stated.
"The principle of ‘innocent until proven guilty’ is integral to citizens receiving a fair trial. Banning sportspeople (as per the de Belin case) clearly taints the jury process."
The party also believes the region cannot cope with a "projected 85,000-population increase over the next 15 years".
"One Nation’s plan for huge cuts to immigration numbers will take much of the population pressure off the region," the plan states.
"Growth should not recommence until the jobs and services deficit has been cleared, including the provision of extra train services and full construction of the F6 link into Sydney."
The party will also promote "a key Illawarra industry" in horse and greyhound racing, remove quotas in policing and toughen parole laws.