UPDATE 2.15pm: A truck driver has been freed from the wreckage and will be flown to a Liverpool Hospital following a collision on the Princes Highway at Bomaderry.
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The 30-year-old man sustained a serious leg injury and was airlifted to Liverpool Hospital in a stable condition.
NSW Ambulance duty operations manager Inspector Chris Lahene said being called to any road crash was always challenging especially when paramedics needed to treat multiple patients.
"Our four paramedic crews and two specialist medical teams did a fantastic job to safely extricate both patients, they provided ongoing treatment before transporting both patients hospital in a stable condition," he said.
"Please take extra care when you get behind the wheel of any vehicle.'
"This had the potential to be fatal."
The Princes Highway remains closed between Berry and Bomaderry, with motorists able to use Belinda Street, Crooked River Road and Bolong Road instead.
Motorists are also advised to allow plenty of extra time to travel through this area.
UPDATE: A driver trapped inside his car was also freed and was suffering from minor leg injuries.
The 50-year-old man was transported by helicopter to St George Hospital in a stable condition.
The truck driver was trapped, with Fire and Rescue crews expected to take half an hour to free him as they try to get between the truck and guard rail.
Crash investigators are on scene and the road is expected to be closed for hours.
EARLIER: Two drivers are trapped after a serious collision between a car and truck on the Princes Highway, Bomaderry.
The highway is closed in both directions between Bolong Road and Meroo Road as the crash occurred close to Silos Estate Berry about 11.45am.
The driver of the car has leg and abdominal pain while the truck driver may have a possible broken leg, however paramedics are unable to fully assess the patient.
To ambulance helicopters are en route.
South Coast Police are also on scene along with Fire and Rescue crews who are working to free the drivers.
Light vehicles travelling north are being diverted via Bolong Road and light vehicles travelling south are diverting via Meroo Road.
Heavy vehicles are being parked.
Motorists are advised to allow extra travel time and exercise caution.
A small spill has also occurred as a result of the crash, which crews are working to render the area safe.
More to come.
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