Two cases in overseas travellers in hotel quarantine were also diagnosed, bringing the total number of cases in NSW to 4,144.
Three of the local cases are a family who attend the Greater Beginnings Childcare Centre in Oran Park, and another is an educator who works at this centre, NSW Health said.
All four cases are close contacts of a known case linked to the Oran Park cluster, which now numbers 18.
All staff or children who attended Great Beginnings Childcare Centre between October 2-13 are considered close contacts and must get tested immediately and self-isolate for a full 14 days from when they last attended.
They must stay isolated for their full isolation period regardless of their test result. Contact tracing and investigations are continuing.
The fifth locally acquired case today is a student who attends Oran Park High School.
Staff and students have been asked to self-isolate. Contact tracing has commenced and the school will be thoroughly cleaned over the weekend.
This student is a close contact of a known confirmed case linked to the Liverpool Private Clinic cluster which now numbers 11 cases.
One new case today visited Woolworths Oran Park on Oran Park Drive, on Friday 12 October from 7pm to 7:30pm. Anyone who was at this store during this time is considered a casual contact and must monitor for symptoms and get tested immediately if they develop.
There were 14,378 tests reported to 8pm last night, compared with 16,391 in the previous 24 hours.