Left-handed Pooran smashed six sixes and four boundaries but his unbeaten 62 off 33 balls could only carry the West Indies to 4-150.

Pakistan, who'd been put into bat, had earlier scored 8-157 with captain Babar Azam (51) and Mohammad Rizwan (46) continuing to score heavily up front.

Jason Holder grabbed 4-26 and Dwayne Bravo got the wickets of Mohammad Hafeez and Fakhar Zaman off successive deliveries as Pakistan lost six wickets for 23 runs in their last four overs.

Rizwan and Azam combined in a 67-run second wicket stand before Rizwan was run out in the 15th over.

Holder returned in the 17th over and Azam was out caught behind after a television referral, leaving the Pakistan captain to walk off the field in disbelief.

The West Indies power-hitters couldn't mount a charge against the experienced offspin of Hafeez, who conceded just six runs off his four overs and bowled Andre Fletcher with his second delivery.

Legspinner Shadab Khan (0-22) also gave away just one boundary that strangled the West Indies' run chase on a slow pitch.

"We were 10-15 runs short, but our bowlers bowled very well, and I think we should give them credit," Azam said.

"Hafeez showed his experience in the powerplay and as captain it pleased me a lot."

When Ewin Lewis had to retire hurt due to cramps after scoring 35 off 33 balls, West Indies still needed 82 runs off the last six overs.

While Kieron Pollard couldn't find boundaries against the pace, Pooran timed the ball well and hit his sixes against fast bowlers Mohammad Wasim, Shaheen Afridi and Hasan Ali.

"I thought the way the bowlers bounced back shows we're consistent with the ball," Pollard said.

"We could have taken a few more singles. There are things we continue to look at, and it's all about improvement as the games go on. We were on the losing end today, but all hope isn't lost."

The first T20 was washed out in Barbados on Wednesday. Guyana hosts the remaining two T20s on Sunday and next Tuesday, followed by a two-Test series in Jamaica.

Australian Associated Press