"Anxiety-inducing" is how Edward Birt, Chief Operating Officer at the Disability Trust, described NSW opening up on Monday.
"It's certainly a bit of a worrying time, as well as an exciting time," he said.
"People are stoked to see programs, shops and activities open up, but from what we've seen in other countries we know after opening up people with disability are overrepresented in the statistics around infections, hospitalisations and deaths."
According to advocacy group People With Disability Australia, just over a third of NDIS participants, less than two-thirds of NDIS participants in shared residential accommodation and just over half of NDIS screened support workers have received two vaccine doses.
"Rather than vaccine hesitancy, the barriers to vaccination that people with disability are experiencing are more likely to be caused by lack of support, lack of access and supply issues," Ms Connor said.
Mr Birt agreed, and said some people with disability were isolated from the support networks that could help them access a vaccine.
He said in the interim it was important for people who are able to be out and about to continue to care for those who are more vulnerable.
"The best way to do that is by looking after yourself," he said.
"Wear a mask, wash your hands, stay home if you're not feeling well, get tested and continue to contain these infections.
"If you have a neighbour who is a bit isolated, put them in touch with services that can help, or see if you can get them to reach out to their local GP.
"We all need to look after each other, and that's how we're going to stay safe coming out of this."