A man's been taken to hospital in a serious condition after being stabbed in the head at Campbelltown on Sunday Morning.
About 10.10am, emergency services were called to a motor-inn on Queen Street, following reports of a fight between two men.
Witnesses told police one man stabbed the other before fleeing the scene in a white Toyota Camry Altise.
The Camry was found a short time later on Lugarno Street in the nearby suburb of Leumeah.
The injured man was treated by NSW Ambulance paramedics before being taken to Liverpool Hospital in a serious condition.
Two crime scenes have been established on Queen and Lugarno streets and as of 1pm Sunday, a search was underway for the alleged offender.
Police believe the men are known to each other.